- Overcome any clinical challenge with this comprehensive and up-to-date neurosurgical reference, and ensure the best outcomes for your patients.
- Rely on this single source for convenient access to the definitive answers you need in your practice.
New to this edition:
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- Successfully perform functional and restorative neurosurgery with expert guidance on the diagnostic aspects, medical therapy, and cutting-edge approaches shown effective in the treatment of tremor, Parkinson's disease, dystonia, and psychiatric disorders.
- Sharpen your neurosurgical expertise with updated and enhanced coverage of complication avoidance and intracranial pressure monitoring, epilepsy, neuro-oncology, pain, peripheral nerve surgery, radiosurgery/radiation therapy, and much more.
- Master new techniques with nearly 100 surgical videos online of intraoperative procedures including endoscopic techniques for spine and peripheral nerve surgery, the surgical resection for spinal cord hemangiomas, the resection of a giant AVM; and the radiosurgical and interventional therapy for vascular lesions and tumors.
- Confidently perform surgical techniques with access to full-color anatomic and surgical line drawings in this totally revised illustration program.
- Get fresh perspectives from new section editors and authors who are all respected international authorities in their respective neurosurgery specialties.
- Conveniently search the complete text online, view all of the videos, follow links to PubMed, and download all images at www.expertconsult.com.
Table of Contents:
Volume I:
Section 1. Introduction to Neurological Surgery
Part 1. History
Chapter 1. Historical Overview of Neurosurgery
Part 2. Basic Science
Chapter 2. Surgical Anatomy of the Brain
Chapter 3. Molecular Biology Primer for Neurosurgeons
Chapter 4. Neuroembryology
Chapter 5. Stem Cell Biology in the Central Nervous System
Chapter 6. Neurons and Neuroglia
Chapter 7. Cellular Mechanisms of Brain Energy Metabolism
Chapter 8. Blood-Brain Barrier
Chapter 9. Cerebral Edema
Chapter 10. Physiology of the Cerebrospinal Fluid and Intracranial Pressure
Chapter 11. Neurosurgical Epidemiology and Outcomes Assessment
Part 3. Approach to the Patient
Chapter 12. Altered Consciousness
Chapter 13. Neuroopthalmology
Chapter 14. Neurotology
Chapter 15. Neurourology
Chapter 16. Neurophychological Testing
Part 4. Radiologic Fundamentals
Chapter 17. Computed Tomography and Magnetic Resonance Imaging of the Brain
Chapter 18. Radiology of the Spine
Chapter 19. Physiologic Evaluation of the Brain with Magnetic Resonance Imaging
Chapter 20. Molecular Imaging of the Brain with Positron Emission Tomography
Section 2: General Neurosurgery
Part 1. Perioperative Care
Chapter 21. Neuroanesthesia: Preoperative Evaluation
Chapter 22. Avoidance of Complications in Neurosurgery
Chapter 23. INtracranial Pressure Monitoring
Chapter 24. Principles of Neurocritical Care
Part 2. General Principles and Surgical Techniques
Chapter 25. Surgical Planning: Overview
Chapter 26. Positioning for Cranial Surgery
Chapter 27. Patient Positioning for Spinal Surgery
Chapter 28. Positioning in Peripheral Nerve Surgery
Chapter 29. Incisions and Closures
Chapter 30. Advantages and Limitations of Cranial Endoscopy
Chapter 31. Thorascopic Spine Surgery
Chapter 32. Cranioplasty
Part 3. Geriatric Neurosurgery
Evaluation of Adult Hydrocephalus
Chapter 33. Production and Flow of Cerebrospinal Fluid
Chapter 34. Clinical Evaluation of Adult Hydrocephalus
Management of Adult Hydrocephalus
Chapter 35. Shunting
Chapter 36. Adult Hydrocephalus: The Role of Endoscopic Third Ventriculostomy
Subdural Hematomas
Chapter 37. Pathophysiology of Subdural Hematomas
Chapter 38. Medical and Surgical Management of Chronic Subdural Hematomas
Part 4. Infection
Chapter 39. Basic Science of Central Nervous System Infections
Chapter 40. Postoperative Infections of the Head and Brain
Chapter 41. Postoperative Infections of the Spine
Chapter 42. The Use and Misuse of Antibiotics in Neurosurgery
Chapter 43. Brain Abscess
Chapter 44. Meningitis and Encephalitis
Chapter 45. Acquired Immune Deficiency Syndrome
Chapter 46. Parasitic Infections
Chapter 47. Surgical Risk of Transmittable Diseases
Section 3: Epilepsy
Part 1. Basic Science of Epilepsy
Chapter 48. Epilepsy Surgery Overview
Chapter 49. Elecrophysiologic Properties of the Mammalian Central Nervous System
Chapter 50. Animal Models of Epilepsy
Chapter 51. Malformations of Cortical Development
Part 2. Approach to the Patient
Chapter 52. Diagnosis and Classification of Seizures and Epilepsy
Chapter 53. Antiepileptic Medications: Principles of Clinical Use
Part 3. Preoperative Evaluation for Epilepsy
Chapter 54. Continuous Electroencephalography in Neurological-Neurosurgical Intensive Care: Applications and Value
Chapter 55. Neuroradiologic Evaluation for Epilepsy Surgery
Chapter 56. Evaluation of Patients for Epilepsy Surgery
Part 4. Intraoperative Mapping and Monitoring for Cortical Resections
Chapter 57. Motor, Sensory, and Language Mapping and Monitoring for Cortical Resections
Chapter 58. Auditory Language Mapping
Chapter 59. Investigation of Human Cognition in Epilepsy Surgery Patients
Part 5. Specific Operative Approaches
Chapter 60. Intracranial Monitoring
Chapter 61. Surgery for Extratemporal Lobe Epilepsy
Chapter 62. Standard Temporal Lobectomy
Chapter 63. Selective Amygdalohippocampectomy
Chapter 64. Tailored Resections for Epilepsy
Chapter 65. Topectomy and Multiple Subpial Transection
Chapter 66. Hemispheric Disconnection Procedures
Chapter 67. Vagus Nerve Stimulation for INtractable Epilepsy
Chapter 68. Radiosurgical Treatment of Epilepsy
Chapter 69. Deep Brain Stimulation for Epilepsy
Chapter 70. Epilepsy Surgery: Outcome and Complications
Section 4: Functional Neurosurgery
Part 1. Overview
Chapter 71. Introduction
Part 2. Basic Science of Movement Disorders
Chapter 72. Anatomy and Synaptic Connectivity of the Basal Ganglia
Chapter 73.Rationale for Surgical Interventions in Movement Disorders
Chapter 74. Neuropathology of Movement Disorders
Part 3. Neurology of Movement Disorders
Chapter 75. Clinical Overview of Movement Disorders
Chapter 76. Patient Selection Criteria for Deep BRain Stimulation in Movement Disorders
Chapter 77. Functional Imaging in Movement Disorders
Part 4. Surgery for Movement Disorders
Chapter 78. Surgical Management of Tremor
Chapter 79. Pallidal Interventions for Parkinson's Disease
Chapter 80. Subthalamic Deep Brain Stimulation for Parkinson's Disease
Chapter 81. Subthalamotomy in Parkinson's Disease: Indications and Outcome
Chapter 82. Deep Brain Stimulation for Dystonia
Chapter 83. Deep Brain Stimulation: Mechanisms of Action
Chapter 84. Emerging and Experimental Neurosurgical Treatments for Parkinson's Disease
Chapter 85. Selective Peripheral Denervation for Cervical Dystonia
Part 5. Surgery for Psychiatric Disorders
Chapter 86. A History of Psychosurgery
Chapter 87. Surgery for Tourette's Syndrome
Chapter 88. Surgery for Obsessive-Compulsive Disorder
Chapter 89. Surgical Treatment of Major Depression
Part 6. Surgical Interventions for Spasticity
Chapter 90. Ablative Surgery for Spasticity
Chapter 91. Management of Spasticity by Central Nervous System Infusion Techniques
Part 7. Miscellaneous
Chapter 92. Treatment of Intractable Vertigo
Chapter 93. Treatment Applications of Cortical Stimulation
Chapter 94. Neuroprosthetics
Volume 2
Section 5: Oncology
Part 1. Overview
Chapter 95. Brain Tumors: General Considerations
Part 2. basic Science of Neurooncology
Chapter 96. Brain Tumors: An Overview of Current Histopathologic Classifications
Chapter 97. Brain Tumor Immunology and Immunotherapy
Chapter 98. Brain Tumor Stem Cells
Chapter 99. Proliferation Markers in the Evaluation of Giliomas
Chapter 100. Molecular Genetics and the Development of Targets for Gilioma Therapy
Chapter 101. Growth Factors in Glial Tumors
Chapter 102. The Genetic Origins of Brain Tumors
Chapter 103. Invasion in Malignant Glioma
Chapter 104. Angiogenesis and Brain Tumors: Molecular Targets and Molecular Scalpels
Chapter 105. Barriers to Delivery of Therapeutics to Brain Tumors
Chapter 106. Epidemiology of Brain Tumors
Chapter 107. Gene- and Viral-Based Therapies for Gliomas
Part 3. Approach to the Patient
Chapter 108. Clinical Features: Neurology of Brain Tumor and Paraneoplastic Disorders
Chapter 109. Radiologic Features of Central Nervous System Tumors
Chapter 110. Endovascular Techniques for Tumor Embolization
Chapter 111. Brain Tumors During Pregnancy
Chapter 112. Principles of Chemotherapy
Chapter 113. Brain Tumor Outcome Studies: Design and Interpretation
Chapter 114. Frame and Frameless Stereotactic Brain Biopsy
Part 4. Surgical Considerations
Chapter 115. Basic Principles of Cranial Surgery for Brain Tumors
Chapter 116. Basic Principles of Skull Base Surgery
Chapter 117. Surgical Complications of Brain Tumors and Their Avoidance
Chapter 118. Navigation for Brain Tumors
Chapter 119. Endoscopic Approaches to Brain Tumors
Chapter 120. Intraoperative Magnetic Resonance Imaging
Part 5. Intrinsic Tumors
Chapter 121. Low-Grade Gliomas: Astrocytoma, Oligodendroglioma, and Mixed Glioma
Chapter 122. Malignant Gliomas: Anaplastic Astrocytoma, Glioblastoma Multiforme, Gliosarcoma
Chapter 123. Unusual Gliomas
Chapter 124. Primitive Neuroectodermal Tumors
Chapter 125. Pineal Tumors
Chapter 126. Medulloblastoma
Chapter 127. Intracranial Ependymomas in Adults
Chapter 128. Hemangioblastomas
Chapter 129. Central Nervous System Lymphoma
Chapter 130. Mesastatic Brain Tumors
Part 6. Extrinsic Tumors
Chapter 131. Meningiomas
Chapter 132. Meningeal Sarcoma and Meningeal Hemangiopericytoma
Chapter 133. Acoustic Neuroma
Chapter 134. Pituitary Tumors: Functioning and Nonfunctioning
Chapter 135. Craniopharyngioma
Chapter 136. Epidermoid, Dermoid, and Neurenteric Cysts
Chapter 137. Neoplastic Meningitis
Part 7. Ventricular Tumors
Chapter 138. Ventricular Tumors
Part 8. Skull and Skull Base Tumors
Chapter 139. Overview of skull Base Tumors
Chapter 140. Chordomas and Chondrosarcomas
Chapter 141. Glomus Tumors
Chapter 142. Neoplasms of the Paranasal Sinuses
Chapter 143. Esthesioneuroblastoma
Chapter 144. Trigeminal Schwannomas
Chapter 145. Juvenile Nasal Angiofibroma
Chapter 146. Osseous Tumors
Chapter 147. Tumors of the Orbit
Chapter 148. Skull Tumors
Chapter 149. Scalp Tumors
Part 9. Nonneoplastic Disorders Mimicking Brain Tumors
Chapter 150. Pseudotumor Cerebri
Chapter 151. Sarcoidosis, Tuberculosis, and Xanthogranuloma
Chapter 152. Demyelinating Disease
Section 6: Pain
Part 1. Overview
Chapter 153. Pain: General HistoricalConsiderations
Part 2. Basic Science
Chapter 154. Anatomy and Physiology of Pain
Chapter 155. Molecular Basis of Nociception
Part 3. Nonsurgical Therapy
Chapter 156. Apporach to the Patient with Chronic Pain
Chapter 157. Pharmacologic Treatment of Pain
Chapter 158. Management of Pain by Anesthetic Technique
Part 4. Treatment of Trigeminal Neuralgia
Chapter 159. Evidence-Based Approach to the Treatment of Facial Pain
Chapter 160. Trigeminal Neuralgia: Diagnosis and Nonoperative Management
Chapter 161. Percutaneous Procedures for Trigeminal Neuralgia
Chapter 162. Stereotactic Radiosurgery for Trigeminal Neuralgia
Chapter 163. Microvascular Decompression for Trigeminal Neuralgia
Part 5. Surgical Procedures for Nontrigeminal Pain
Chapter 164. Neurosurgical Management of Intractable Pain
Neuromodulation
Chapter 165. Evidence Base: Neurostimulation for Pain
Chapter 166. Peripheral Nerve Stimulation for Neuropathic Pain
Chapter 167. Spinal Cord Stimulation
Chapter 168. Motor Cortex Stimulation
Destructive Procedures
Chapter 169. Evidence Base for Destructive Procedures
Chapter 170. Diagnosis and Management of Painful Neuromas
Chapter 171. Dorsal Root Entry Zone Lesions
Chapter 172. Percutaneous Cordotomy and Trigeminal Tractotomy-Nucleotomy
Section 7. Pediatrics
Part 1. Overview and Approach
Chapter 173. Neuroanesthesia in Children
Chapter 174. Neurocritical Care in Children
Part 2. Cranial Development Abnormalities
Chapter 175. Normal and Abnormal Embryology of the Brain
Chapter 176. Encephalocele
Chapter 177. Dandy-Walker Syndrome
Chapter 178. Arachnoid Cysts
Chapter 179. Chiari Malformations
Chapter 180. Craniopagus Twins
Part 3. Craniosynostosis
Chapter 181. Genetics of Craniosynostosis
Chapter 182. Craniosynostosis
Chapter 183. Syndromic Craniosynostosis
Chapter 184. Endoscopic Treatment of Craniosynostosis
Chapter 185. Plagiocephaly
Part 4. Hydrocephalus
Chapter 186. Hydrocephalus in Children: Approach to the Patient
Chapter 187. Infantile Posthemorrhagic Hydrocephalus
Chapter 188. Cerebrospinal Fluid Physiology
Chapter 189. Experimental Hydrocephalus
Chapter 190. Ventricular Shunting Procedures
Chapter 191. Neuroendoscopy
Chapter 192. Cerbrospinal Fluid Devices
Chapter 193. Shunt Infections and Their Treatment
Part 5. Pediatric Cranial and Intracranial Tumors
Chapter 194. General Approaches and Considerations for Pediatric Brain Tumors
Chapter 195. Optic Pathway HYpothalamic Gliomas
Chapter 196. Thalmic Tumors
Chapter 197. Choroid Plexus Tumors
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Part 6. Vascular Disease
Part 7. Head and Brain Trauma
Part 8. Spine Disorders in Children
Part 9. Cerebral Palsy, Spasticity, and Dystonia
Volume 3:
Section 8: Peripheral Nerve
Part 1. Overview
Part 2. Basic Science of Peripheral Nerve Disorders
Part 3. Approach to the Patient with Peripheral Nerve Disorders
Part 4. Management of Peripheral Nerve Entrapment
Part 5. Management and Repair of Peripheral Nerve Injuries
Part 6. Management of Peripheral Nerve Tumors
Part 7. Management of Pain and Complications in Peripheral Nerve Surgery
Section 9: Radiation
Part 1. Overview
Part 2. Basic Science of Radiotechniques
Part 3. Fractionated Radiation Therapy
Part 4. Techniques of Radiosurgery
Part 5. Intracranial Stereotactic Radiosurgery
Part 6. Extracranial Stereotactic Radiosurgery
Section 10: Spine
Part 1. Overview
Part 2. Basic Science of the Spine
Part 3. Approach to the Patient
Part 4: Infection of the Spine
Part 5. Degenerative Disease of the Spine
Part 6. Congenital and Developmental Anomalies of the Spine
Part 7. Techniques for Spinal Procedures
Part 8. Instrumentation in Spinal surgery
Part 9. Tumors of the Spine
Part 10. Spinal Trauma
Volume 4:
Section 11: Trauma
Part 1. Introduction
Part 2. Basic and Clinical Science
Part 3. Radiology in Traumatic Brain Surgery
Part 4. Management of Traumatic Brain Surgery
Part 5. Sequelae and Outcome in Traumatic Brain Surgery
Section 12: Vascular
Part 1. Overview: basic Science, Medical Management, and Radiologic Evaluation
Part 2. Occlusive Vascular Disease
Part 3. Nonlesional Spontaneous INtracerbral Hemorrhage
Part 4. Hemorrhagic Vascular Disease
Part 5. True Arteriovenous Malformations
Part 6. Arteriovenous Fistulas
Part 7. Cavernomas
Part 8. Arteriovenous Malformations and Fistulas of the Apine
Part 9. Miscellaneous