Table of Contents:

Part I:  History of Parkinson's Disease Therapy

Chapter 1.     History of the Medical Therapy of Parkinson's Disease

Chapter 2.     History of Surgery for Parkinson's Disease

Part II:  Assessment of Signs and Symptoms of Parkinson's Disease

Chapter 3.     Clinical Assessments

Chapter 4.     Magnetic Resonance Imaging and Positron Emission Tomography Investigations

Part III:  Levodopa Therapy

Chapter 5.     Is Levodopa Toxic?

Chapter 6.     Levodopa Therapy

Chapter 7.     Levodopa Infusion

Part IV:  Dopamine Agonists

Chapter 8.     Bromocriptine

Chapter 9.     Pergolide

Chapter 10.   Pramipexole

Chapter 11.   Ropinirole

Chapter 12.   Cabergoline

Chapter 13.   Apomorphine and Rotigotine

Part V:  COMT Inhibitors

Chapter 14.   Tolcapone

Chapter 15.   Entacapone

Part VI:  Other Antiparkinsonian Medications

Chapter 16.   Anticholinergics

Chapter 17.   Selegiline

Chapter 18.   Amantadine

Part VII:  Ablative Surgeries

Chapter 19.   Thalamotomy

Chapter 20.   Pallidotomy

Chapter 21.   Subthalamotomy

Part VIII:  Deep Brain Stimulation

Chapter 22.   Thalamic Deep Brain Stimulation

Chapter 23.   Globus Pallidal Deep Brain Stimulation

Chapter 24.   Subthalamic Nucleus Deep Brain Stimulation

Part IX:  Other Treatment Options

Chapter 25.   Cell Transplantation

Chapter 26.   Electroconvulsive Therapy

Chapter 27.   Functional Radiosurgery in Movement Disorders

Chapter 28.   Transcranial Magnetic Stimulation

Part X:  Therapy for Nonmotor Symptoms

Chapter 29.   Autonomic Nervous System Disturbances

Chapter 30.   Sleep Problems

Chapter 31.   Psychosis and Dementia

Chapter 32.   Anxiety and Depression

Part XI:  Nonmedical Management

Chapter 33.   Diet and Nutrition

Chapter 34.   Speech, Voice, and Swallowing Disorders

Chapter 35.   Physical and Occupational Therapy

Part XII:  Investigational Therapies

Chapter 36.   New and Experimental Drug Treatments

Chapter 37.   Mitochondrial Dysfunction and Therapies

Chapter 38.   Trophic Factors:  Potential Therapies

Chapter 39.   Neural Stem Cell Therapy