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From the Publisher: Since its introduction as a new clinical entity in 1992, the Brugada syndrome has attracted great interest because of its high incidence in many parts of the world and its association with high risk for sudden death in infants, children and young adults. Recent years have witnessed an exponential rise in the number of reported cases and a striking proliferation of papers serving to define the clinical, genetic, cellular, ionic and molecular aspects of the disease. This text delineates the diagnostic criteria for the syndrome and deals with risk stratification and approaches to therapy. The book handles this topic in a very comprehensive manner with the clinical, molecular, genetic, and cellular aspects of the Brugada syndrome authored by the leading experts in the field. Table of Contents: Chapter 1. Brugada Syndrome: Overview Chapter 2. History of the Brugada Syndrome Chapter 3. Biophysical Analysis of Mutant Sodium Channels Chapter 4. Molecular Genetics of the Brugada Syndrome Chapter 5. Cellular Mechanisms Underlying the Brugada Syndrome Chapter 6. Brugada Syndrome: Diagnostic Criteria Chapter 7. Value of 12 Lead Electrocardiogram and Derived Methodologies in the Diagnosis of Brugada Disease Chapter 8. Brugada Syndrome: Relationship to Other Arrhythmogenic Syndromes Chapter 9. ST Segment Elevation and Sudden Death in the Athlete Chapter 10. Brugada Syndrome: Role of Genetics in Clinical Practice Chapter 11. Genotype-Phenotype Relationship in the Brugada Syndrome Chapter 12. Gender Differences in Brugada Syndrome Chapter 13. Predisposing Factors Chapter 14. Acquired Forms of Brugada Syndrome Chapter 15. Atrial Tachyarrhythmias in Brugada Syndrome Chapter 16. Prognosis in Individuals with Brugada Syndrome Chapter 17. Treatment of Brugada Syndrome with and Implantable Cardioverter Defibrillator Chapter 18. Pharmacologic Approach to Therapy of Brugada Syndrome: Quinidine as an Alternative to ICD Therapy? Chapter 19. Potential for Ablation Therapy in Patients with Brugada Syndrome
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