Table of Contents:

Part I:  Pathophysiology

Chapter 1.    Immunoglobulins

Chapter 2.     Multiple Myeloma and Plasma Cells:  Cell-Cycle and Apoptotic Controls

Chapter 3.     The Molecular Biology of Multiple Myeloma

Chapter 4.     Cytokines, Cytokine Receptors, and Signal Transduction in Human Multiple Myeloma

Chapter 5.     Cytogenetics of Multiple Myeloma

Chapter 6.     Gene Expression Profiling and Multiple Myeloma

Part II:  Clinical Features

Chapter 7.     Multiple Myeloma:  A History

Chapter 8.     Epidemiology of Multiple Myeloma

Chapter 9.     Clinical Presentation, Laboratory Diagnosis, and Indications for Treatment

Chapter 10.   Radiologic Features of Multiple Myeloma

Chapter 11.   Prognostic Factors and Classification for Multiple Myeloma (Contribution to Clinical Management)

Part III:  Therapy of Myeloma

Chapter 12.   Conventional-Dose Chemotherapy of Myeloma

Chapter 13.   High-Dose Therapy in Multiple Myeloma

Chapter 14.   Novel Therapies for Multiple Myeloma

Chapter 15.   Management of Skeletal Complications

Chapter 16.   Management of Renal, Hematologic, and Infectious Complications

Chapter 17.   Neurological Manifestations of Myeloma and Their Managment

Chapter 18.   Myeloma:  Patient and Care Giver Perspectives

Part IV:  Other Disorders Associated with Paraproteinemia

Chapter 19.   Monoclonal Gammopathies of Undetermined Significance

Chapter 20.   Plasmacytoma

Chapter 21.   Amyloidosis

Chapter 22.   Heavy Chain Diseases

Chapter 23.   Waldenstrom's Macroglobulinemia