Table of Contents:

Chapter 1.     Developments in Multiple Sclerosis:  Research Overview

Section I:  Morphologic Substrates of Demyelination

Chapter 2.     Morphology of Oligodendrocytes and Myelin

Chapter 3.     Astrocytes:  Structure and Function

Chapter 4.     Molecular Structure of the Myelin Membrane

Section II:  Experimental Aspects of Demyelination

Chapter 5.     The Nature of Immunologic Privilege in the Central Nervous System

Chapter 6.     Experimental Autoimmune Encephalomyelitis

Chapter 7.     Tissue Culture Studies of Demyelination and Remyelination

Chapter 8.     Multiple Sclerosis:  The Role of Pathogens in Demyelination

Chapter 9.     Viral Demyelinating Diseases in Experimental Animals

Chapter 10.   Chlamydia pneumoniae Infection and Its Association with Multiple Sclerosis

Section III:  Cytokines, Chemokines, and Interferons

Chapter 11.   Role of Cytokines in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

Chapter 12.   Chemokines and Their Receptors in Multiple Sclerosis

Chapter 13.   Interferons in Multiple Sclerosis

Section IV:  Pathology

Chapter 14.   The Pathology of Multiple Sclerosis and its Variants

Chapter 15.   Pathology of Multiple Sclerosis as Revealed by In Vivo Magnetic Resonance-Based Approaches

Chapter 16.   Mechanisms of Repair, Adaptation, and Recovery of Function in Multiple Sclerosis