From the Publisher:             

     Since their discovery in the 1960s, methicillin-resistant S. aureus (MRSA) strains continue to present unique challenges to clinicians, microbiologists, and the molecular biologists around the world. These organisms are typically resistant to several other antimicrobial agents, including aminoglycosides, chloramphenicol, clindamycin, fluoroquinolones and macrolides and are susceptible only to vancomycin. In fact there is increasing evidence that this susceptibility will soon disappear.

     In this book, internationally renown authors comprehensively review all aspects of MRSA research. Topics covered include strategies for the detection and typing of MRSA strains, epidemiological characterisation, molecular evolution of MRSA, vancomycin resistant S. aureus, mechanisms of methicillin resistance, virulence mechanisms in MRSA pathogenesis, recommended treatment of MRSA infections and options for the prevention and control of MRSA infections.

An essential text for all scientists and clinicians with an interest in the Staphylococcus aureus or antibiotic resistance.

Key Features:

• Detailed Discussions of Cutting Edge Topics
• Expert International Authors
• Useful Index
• Up-To-Date
• Broad Coverage

Table of Contents:

Chapter 1.     Introduction

Chapter 2.     Detection of MRSA

Chapter 3.     Mechanisms of Methicillin Resistance

Chapter 4.     MRSA Resistance Mechanisms and Surveillance Data for Non-betalactams and Non-glycopeptides

Chapter 5.     Molecular Approaches for the Epidemiological Characterization of Staphylococcus aureus Strains

Chapter 6.     The Molecular Evolution of Methicillin Resistant Staphylococcus aureus

Chapter 7.     Population Structure of MRSA

Chapter 8.     Vancomycin-Resistant Staphylococcus aureus

Chapter 9.     Virulence Mechanims in MRSA Pathogenesis

Chapter 10.   Small Colony Variants-Another Mechanism by Which Staphylococcus aureus Can Evade the Immune Response and Antimicrobial Therapy

Chapter 11.   Treatment of MRSA Infections

Chapter 12.   Prevention and Control of Methicillin-Resistant Staphylococcus aureus (MRSA)

Chapter 13.   Concluding Remarks

INDEX