Table of Contents:

Part I:  Epidemiology, Clinical Features, and Differential Diagnosis

Chapter 1.     Epidemiology of Idiopathic Pulmonary Fibrosis

Chapter 2.     Genetics of Familial Pulmonary Fibrosis and Other Variants

Chapter 3.     Clinical Features and Differential Diagnosis of Idiopathic Pulmonary Fibrosis

Chapter 4.     Pathology of Usual Interstitial Pneumonia

Chapter 5.     Nonspecific Interstitial Pneumonia

Chapter 6.     Role of Physiological Assessment in Usual Interstitial Pneumonia

Chapter 7.     Role of High-Resolution Thin Section Computed Tomographic Scanning

Chapter 8.     Other Imaging Techniques for Idiopathic Interstitial Pneumonias

Chapter 9.     Bronchoalveolar Lavage in Interstitial Lung Disease

Chapter 10.   Pulmonary Fibrosis in Connective Tissue Disease   

Part II:  Pathogenesis and Mechanisms

Chapter 11.   Cytokine Phenotypes and the Progression of Chronic Pulmonary Fibrosis

Chapter 12.   CXC Chemokines in Angiogenesis Related to Pulmonary Fibrosis

Chapter 13.   Role of Polymorphonuclear Leukocytes in the Pathogenesis of Idiopathic Pulmonary Fibrosis

Chapter 14.   Integrins and Pulmonary Fibrosis

Chapter 15.   Oxidants and Antioxidants in Idiopathic Pulmonary Fibrosis

Chapter 16.   Fibrin Turnover in Pulmonary Fibrosis

Chapter 17.   Arachidonic Acid Metabolites:  Potential Mediators and Therapeutic Targets in Fibrotic Lung Disease

Chapter 18.   Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Pulmonary Fibrosis

Chapter 19.   Extracellular Matrix

Chapter 20.   Role of Fibroblasts and Myofibroblasts in Idiopathic Pulmonary Fibrosis

Chapter 21.   Peptide and Provisional Matrix Signals in Idiopathic Pulmonary Fibrosis

Chapter 22.   Role of Alveolar Type II Epithelial Cells in Pulmonary Fibrosis

Chapter 23.   Surfactant Proteins in the Pathophysiology of Pulmonary Fibrosis

Chapter 24.   Bronchiolar Epithelium in Idiopathic Pulmonary Fibrosis/ Usual Interstitial Fibrosis

Chapter 25.   Role of Viruses in the Pathogenesis of Pulmonary Fibrosis

Part III:  Current and Future Therapies

Chapter 26.   Current Treatment Options

Chapter 27.   Future Directions in the Treatment of Idiopathic Pulmonary Fibrosis