Table of Contents:

VOLUME 1:

Part I:  History

Chapter 1.     Pediatric Hematology in Historical Perspective

Part II:  Neonatal Hematology

Chapter 2.     The Neonatal Erythrocyte and its Disorders

Chapter 3.     Immune Hemolytic Disease

Chapter 4.     Disorders of Bilirubin Metabolism

Chapter 5.     Developmental Hemostasis:  Relevance to Newborns and Infants

Part III:  Bone Marrow Failure

Chapter 6.     The Anatomy and Physiology of Hematopoiesis

Chapter 7.     Acquired Aplastic Anemia

Chapter 8.     Inherited Bone Marrow and Stem Cell Transplantation

Chapter 9.     Principles of Bone Marrow and Stem Cell Transplantation

Part IV:  Disorders of Erythrocyte Production

Chapter 10.   A Diagnostic Approach to the Anemic Patient

Chapter 11.   Megaloblastic Anemia

Chapter 12.   Disorders of Iron Metabolism and Sideroblastic Anemia

Chapter 13.   The Porphyrias

Part V:  Hemolytic Anemias

Chapter 14.   Autoimmune Hemolytic Anemia

Chapter 15.   Disorders of the Erythrocyte Membrane

Chapter 16.   Pyruvate Kinase Deficiency and Disorders of Glycolysis

Chapter 17.   Glucose-6-Phosphate Dehydrogenase Deficiency and Hemolytic Anemia

 Part VI:  Disorders of Hemoglobin

Chapter 18.   Hemoglobins:  Normal and Abnormal

Chapter 19.   Sickle Cell Disease

Chapter 20.   The Thalassemias

Part VII:  The Phagocyte System

Chapter 21.   The Phagocyte System and Disorders of Granulopoiesis and Granulocyte Function

VOLUME 2:

Part VIII:  The Immune System

Chapter 22.   Cell-Mediated and Humoral Immunity and the Regulation of Immune Responses

Chapter 23.   Primary Immunodeficiency Diseases

Part IX:  Oncology

Chapter 24.  Epidemiology of Leukemia in Childhood

Chapter 25.  Chromosomal Abnormalities in Childhood Hematologic Malignant Disease

Chapter 26.  Acute Lymphoblastic Leukemia

Chapter 27.   Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease in Children

Chapter 28.  Acute Leukemia in Infants

Chapter 29.   The Molecular Basis of Hematologic Malignancy

Chapter 30.   Minimal Residual Leukemia

Chapter 31.   Pharmacology of Antineoplastic Agents and Multidrug Resistance

Chapter 32.   Cell, Cytokine, Monoclonal Antibody, and Gene Therapy

Chapter 33.   The Lymphomas and Lymphadenopathy

Chapter 34.   Lymphohistiocytic Disorders

Part X:  Storage Diseases

Chapter 35.   Storage Diseases of the Reticuloendothelial System

Part XI:  Hemostasis

Chapter 36.   Blood Platelets and the Vessel Wall

Chapter 37.   Blood Coagulation

Chapter 38.   The Molecular Basis of Fibrinolysis

Chapter 39.   Clinical and Laboratory Approach to the Patient with Bleeding

Chapter 40.   Inherited Platelet Disorders

Chapter 41.   Hemophilia and von Willebrand Disease

Chapter 42.   Rare Hereditary Coagulation Factor Abnormalities

Chapter 43.   Inherited Disorders of Thrombosis and Fibrinolysis

Chapter 44.   Acquired Platelet Defects

Chapter 45.   Acquired Disorders of Hemostasis

Part XII:  Supportive Therapy

Chapter 46.   Psychologic Aspects of Leukemia and Hematologic Disorders

Chapter 47.   Infectious Complications in Children with Hematological Disorders

Chapter 48.   Transfusion Medicine

Part XIII:  Hematologic Manifestations of Systemic Diseases

Chapter 49.   Hematologic Manifestations of Systemic Diseases

Chapter 50.   Hematologic Manifestations of Systemic Diseases in Children of the Developing World

Appendix:  Reference Values in Early Childhood