This is a review text on endometriosis and its epidemiology, pathogenesis, genetics and treatment. Specifically, it includes sub-topics on its immunologic effects and its impact on fertility and pelvic pain. It is edited by well-known and respected physicians who have assembled a strong group of chapter authors. The topics also include investigative areas in the disease that may improve its characterization and treatment. Particular attention has been paid to research breakthroughs in the pathogenesis of endometriosis.

   The editors’ goals for this text appear to present it as a clinical and research resource. They have been adequately met and the research components make the text unique and useful. It does also have clinical utility. Many of the chapters are written by expert clinicians with great experience in the treatment and clinical research of endometriosis. In that regard the chapters by Drs. Barbieri, Surrey and Germayer/Guidice stand out. The last three chapters are particularly useful for clinicians treating infertile women with the disease.

    As above the unique aspect of this text is the great attention paid to the most current and solid research data, both basic and clinical, on the disease. The chapter on animal models, immunologic aspects and aromatase inhibitors are worthy of being lead review articles in the major journals of our specialty. The references are excellent. Overall I see this text as especially useful in a library setting for medical students/residents through to faculty, and individually for fellows and faculty/clinicians who are actively treating endometriosis patients with infertility and/or pelvic pain.

Ratings: (1-4, 4 being the highest)

Organization of information:    3

Usefulness of book:     3

Suitable for intended audience:    3

Author’s objectives met:      3

Significant number of Figures/ illustrations:     2

Quality of Figures/ illustrations:    2

Table of Contents:

Chapter 1.     Epidemiology of Endometriosis

Chapter 2.     Pathogenesis of Endometriosis:  Peritoneal Endometriosis, Ovarian  Endometriosis, and Rectovaginal Adenomyosis

Chapter 3.     Anatomical Sites of Endometriosis

Chapter 4.     Genetics of Endometriosis

Chapter 5.     Research Aspects of Endometriosis

Chapter 6.     Animal Models for Research on Endometriosis

Chapter 7.     Immunology of Endometriosis and Immunotherapy

Chapter 8.     Serum and Peritoneal Markers for Endometriosis

Chapter 9.     How Does Endometriosis Cause Infertility?

Chapter 10.   Medical Therapy for Endometriosis:  An Overview

Chapter 11.   Treatment with Aromatase Inhibitors

Chapter 12.   Endometriosis:  Medical Treatment with Progestagens

Chapter 13.   Gonadotropin Releasing Hormone Agonist and Antagonist for Endometriosis

Chapter 14.   Management of Endometriosis After Hysterectomy and Bilateral Salpingo-Oophorectomy

Chapter 15.   Treatment of Ovarian Endometrioma

Chapter 16.   Treatment of Endometriosis-Related Pelvic Pain

Chapter 17.   In Vitro Fertilization or Superovulation?  Evidence, Flaws, and Advice

Chapter 18.   Does Endometriosis Affect the Results of In Vitro Fertilization?