The leading reference text entirely devoted to this increasingly significant condition

     Cases of gastroesophageal reflux disease (GERD) and its most sinister complication, Barrett's Esophagus and esophageal adenocarcinoma are on the increase.  The link between this disease and gastrointestinal cancer is also one of the hottest topics in gastroenterology at the moment.

     This text is dedicated to Barrett's esophagus and provides recent evidence and current approaches to patient management.  It has been completely revised, updated and extended to include the latest research findings and describes how these affect day-to-day clinical practice. 

     It includes seven new chapters and even more color images than the last edition.  Each chapter, written by the leading international experts in the field provides clear, didactic guidance on diagnosis, treatment and management of this condition.

     Barrett's Esophagus gives an extensive overview covering epidemiology, screening, pathology, gastroenterology and surgery.  It looks at the precursor lesions leading to the development of Barrett's epithelium, the unique characteristics of Barrett's esophagus, and the consequences of malignant degeneration.  All aspects of diagnosis, secondary prevention, multimodality, and medical and surgical treatment are clearly explained.

     This is a complete guide on the latest thinking on diagnosis and treatment of Barrett's esophagus which can be referred to over and over again.

Table of Contents:

Chapter 1.     Definition and Diagnosis of Barrett's Esophagus

Chapter 2.     The Epidemiology and Prevalence of Barrett's Esophagus

Chapter 3.     Esophageal Adenocarcinoma--Epidemiology and Association with Barrett's Esophagus

Chapter 4.     Pathogenesis of Barrett's Esophagus

Chapter 5.     The Role of Acid and Bile in Barrett's Esophagus

Chapter 6.     Esophageal Motility Abnormalities in Barrett's Esophagus

Chapter 7.     Mucosal Defense in Barrett's Esophagus

Chapter 8.     The Role of Helicobacter pylori in Barrett's Esophagus

Chapter 9.     Molecular Biology of Barrett's Esophagus

Chapter 10.   Histology of Barrett's Esophagus:  Metaplasia and Dysplasia

Chapter 11.   Screening for Barrett's Esophagus:  Targeting High Risk Patients

Chapter 12.   Surveillance of Barrett's Esophagus

Chapter 13.   The Cost Effectiveness of Screening and Surveillance to Decrease Mortality from Esophageal Adenocarcinoma

Chapter 14.   Chromoendoscopy in Barrett's Esophagus

Chapter 15.   Surface Imaging in Barrett's Esophagus:  The Role of High-Resolution Endoscopy, Magnifying Endoscopy, and Related Techniques

Chapter 16.  Emerging Techniques:  Spectroscopy

Chapter 17.   Emerging Techniques:  Optical Coherence Tomography, Confocal Imaging, and Others

Chapter 18.   Medical Management of Barrett's Esophagus

Chapter 19.   Thermal Endoscopic Therapy of Barrett's Esophagus

Chapter 20.   Ablation of Barrett's Esophagus with Laser and Photodynamic Therapy

Chapter 21.   Endoscopic Resection

Chapter 22.   Role of Endoscopic Ultrasound in Barrett's Esophagus and Esophageal Adenocarcinoma

Chapter 23.   Surgical Therapy of Barrett's Esophagus and Cancer

Chapter 24.   Chemoprevention for Barrett's Esophagus

Chapter 25.   Management of High-Grade Intraepithelial Neoplasia in Barrett's Esophagus

Chapter 26.   Esophageal and Gastroesophageal Junction Adenocarcinoma

Chapter 27.   The Options for Palliation of Esophageal Adenocarcinoma